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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1CA
All Species:
67.88
Human Site:
Y78
Identified Species:
99.56
UniProt:
P62136
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62136
NP_001008709.1
330
37512
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Chimpanzee
Pan troglodytes
XP_001151893
326
36742
Y74
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Rhesus Macaque
Macaca mulatta
XP_001117941
427
47327
Y175
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P62137
330
37522
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Rat
Rattus norvegicus
P62138
330
37494
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006190
323
36981
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Frog
Xenopus laevis
Q7SZ10
323
36919
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Zebra Danio
Brachydanio rerio
NP_997875
332
37590
Y78
D
L
L
R
L
F
E
Y
G
G
Y
P
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48461
327
37351
Y76
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Honey Bee
Apis mellifera
XP_392943
329
37410
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Nematode Worm
Caenorhab. elegans
P48727
333
37773
Y77
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Sea Urchin
Strong. purpuratus
XP_791029
330
37658
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
Y75
D
L
L
R
L
F
D
Y
G
G
Y
P
P
Q
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
Y75
D
L
L
R
L
F
E
Y
G
G
Y
P
P
A
A
Baker's Yeast
Sacchar. cerevisiae
P32598
312
35889
Y77
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
A
Conservation
Percent
Protein Identity:
100
95.1
75.1
N.A.
N.A.
99.6
100
N.A.
N.A.
90
90.3
89.7
N.A.
87.5
89.3
90.3
89.3
Protein Similarity:
100
95.4
76.8
N.A.
N.A.
100
100
N.A.
N.A.
93.3
93.3
94.8
N.A.
92.1
93
94.2
94.5
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
100
100
100
93.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
100
100
100
Percent
Protein Identity:
N.A.
72.4
N.A.
73.3
80.6
81.5
Protein Similarity:
N.A.
83
N.A.
85.7
87.5
88.1
P-Site Identity:
N.A.
73.3
N.A.
80
100
93.3
P-Site Similarity:
N.A.
100
N.A.
93.3
100
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
94
0
0
0
0
0
0
88
0
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
82
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
100
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
100
100
0
100
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
100
100
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _